BPC157CLINIC.COM VOL. I  /  SECTION 04

Vol. I / Section 04 / Refs

References

Every citation referenced on the research, dosage, FAQ, and index pages. Numerical order, journal-style.

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Fig. 8. Bound journal volumes, edge-on. Each citation below resolves to a peer-reviewed publication indexed in PubMed, PMC, or the publisher’s DOI registry.

Note on the index

Colophon. Citations are listed in the order they appear on the site. Each entry includes authors, title, journal, year, volume, DOI where available, and a PubMed or PubMed Central URL where available. Where a citation is referenced multiple times on the site, the entry appears once and is referred to by its number throughout.

Citation list

  1. Staresinic M, Sebecic B, Patrlj L, Jadrijevic S, Suknaic S, Perovic D, Aralica G, Zarkovic N, Borovic S, Srdjak M, Hajdarevic K, Kopljar M, Batelja L, Boban-Blagaic A, Turcic I, Anic T, Seiwerth S, Sikiric P. Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth. Journal of Orthopaedic Research. 2003;21(6):976–983. DOI: 10.1016/S0736-0266(03)00110-4  ·  link
  2. Chang CH, Tsai WC, Hsu YH, Pang JHS. Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts. Molecules. 2014;19(11):19066–19077. DOI: 10.3390/molecules191119066  ·  PMC
  3. Krivic A, Anic T, Seiwerth S, Huljev D, Sikiric P. Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: promoted tendon-to-bone healing and opposed corticosteroid aggravation. Journal of Orthopaedic Research. 2006;24(5):982–989. DOI: 10.1002/jor.20096  ·  PubMed
  4. Brcic L, Brcic I, Staresinic M, Novinscak T, Sikiric P, Seiwerth S. Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing. Journal of Physiology and Pharmacology. 2009;60 Suppl 7:191–196. PubMed
  5. Sebecic B, Nikolic V, Sikiric P, Seiwerth S, Sosa T, Patrlj L, Grabarevic Z, Rucman R, Petek M, Konjevoda P, Jadrijevic S, Perovic D, Slaj M. Osteogenic effect of a gastric pentadecapeptide, BPC-157, on the healing of segmental bone defect in rabbits: a comparison with bone marrow and autologous cortical bone implantation. Bone. 1999;24(3):195–202. DOI: 10.1016/s8756-3282(98)00180-x  ·  PubMed
  6. Sikiric P, Seiwerth S, Brcic L, et al. Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia). Full and distended stomach, and vascular response. Inflammopharmacology. 2006;14(5-6):214–221. DOI: 10.1007/s10787-006-1531-7  ·  PubMed
  7. Klicek R, Sever M, Radic B, Drmic D, Kocman I, Zoricic I, et al. Pentadecapeptide BPC 157, in clinical trials as a therapy for inflammatory bowel disease (PL14736), is effective in the healing of colocutaneous fistulas in rats: role of the nitric oxide-system. Journal of Pharmacological Sciences. 2008;108(1):7–17. DOI: 10.1254/jphs.fp0072161  ·  PubMed
  8. Gjurasin M, Miklic P, Zupancic B, Perovic D, Zarkovic K, Brcic L, Kolenc D, Radic B, Seiwerth S, Sikiric P, et al. Peptide therapy with pentadecapeptide BPC 157 in traumatic nerve injury. Regulatory Peptides. 2010;160(1-3):33–41. DOI: 10.1016/j.regpep.2009.11.005  ·  PubMed
  9. Perovic D, Kolenc D, Bilic V, Somun N, Drmic D, Elabjer E, Buljat G, Seiwerth S, Sikiric P. Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats. Journal of Orthopaedic Surgery and Research. 2019;14(1):199. DOI: 10.1186/s13018-019-1242-6  ·  PubMed
  10. Vukojevic J, Milavic M, Perovic D, Ilic S, Cilic AZ, Duran N, Strbe S, Zoricic Z, Filipcic I, Brecic P, Seiverth S, Sikiric P. Pentadecapeptide BPC 157 and the central nervous system. Neural Regeneration Research. 2022;17(3):482–487. DOI: 10.4103/1673-5374.320969  ·  PubMed
  11. He L, Feng D, Guo H, et al. Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs. Frontiers in Pharmacology. 2022;13:1026182. DOI: 10.3389/fphar.2022.1026182  ·  Frontiers
  12. Demirtas H, Ozer A, Yildirim AK, Dursun AD, Sezen SC, Arslan M. Protective Effects of BPC 157 on Liver, Kidney, and Lung Distant Organ Damage in Rats with Experimental Lower-Extremity Ischemia–Reperfusion Injury. Medicina (Kaunas). 2025;61(2):291. DOI: 10.3390/medicina61020291  ·  PMC
  13. Bajramagic S, Sever M, Rasic F, Staresinic M, Skrtic A, Beketic Oreskovic L, et al. Stable Gastric Pentadecapeptide BPC 157 and Intestinal Anastomoses Therapy in Rats — A Review. Pharmaceuticals (Basel). 2024;17(8):1081. DOI: 10.3390/ph17081081  ·  PMC
  14. Matek D, Matek I, Staresinic E, Japjec M, Bojanic I, et al. Stable Gastric Pentadecapeptide BPC 157 as Therapy After Surgical Detachment of the Quadriceps Muscle from Its Attachments for Muscle-to-Bone Reattachment in Rats. Pharmaceutics. 2025;17(1):119. DOI: 10.3390/pharmaceutics17010119  ·  PMC
  15. Lojo N, Rasic Z, Boban Blagaic A, Cesarec V, Drmic D, et al. Pentadecapeptide BPC 157 and its effects on a NSAID toxicity model: diclofenac-induced gastrointestinal, liver, and encephalopathy lesions. Life Sciences. 2011. DOI: 10.1016/j.lfs.2011.06.024  ·  ScienceDirect
  16. Vasireddi N, Hahamyan H, Salata MJ, Karns M, Calcei JG, Voos JE, Apostolakos JM. Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review. HSS Journal. 2025. DOI: 10.1177/15563316251355551  ·  Sage
  17. McGuire FP, Martinez R, Lenz A, Skinner L, Cushman DM. Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing. Current Reviews in Musculoskeletal Medicine. 2025;18(12):611–619. DOI: 10.1007/s12178-025-09990-7  ·  PMC
  18. Jozwiak M, Bauer M, Kamysz W, Kleczkowska P. Multifunctionality and Possible Medical Application of the BPC 157 Peptide — Literature and Patent Review. Pharmaceuticals (Basel). 2025;18(2):185. DOI: 10.3390/ph18020185  ·  PMC
  19. Vukusic D, Zenko Sever A, Sever M, Drmic D, Milavic M, et al. Duodenocolic fistula healing by pentadecapeptide BPC 157 in rats. A cytoprotection viewpoint. Journal of Physiology and Pharmacology. 2024;75(1). DOI: 10.26402/jpp.2024.1.09  ·  PubMed
  20. Hsieh MJ, Liu HT, Wang CN, Huang HY, Lin Y, Ko YS, Wang JS, Chang VHS, Pang JHS. Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway. Scientific Reports. 2020;10(1):17078. DOI: 10.1038/s41598-020-74022-y  ·  Nature
  21. Sikiric P, Separovic J, Buljat G, Anic T, Stancic-Rokotov D, Mikus D, et al. The antidepressant effect of an antiulcer pentadecapeptide BPC 157 in Porsolt’s test and chronic unpredictable stress in rats. A comparison with antidepressants. Journal of Physiology, Paris. 2000;94(2):99–104. DOI: 10.1016/s0928-4257(00)00148-0  ·  PubMed
  22. Boban Blagaic A, Blagaic V, Mirt M, Jelovac N, Dodig G, Rucman R, Petek M, Turkovic B, Anic T, Dubovecak M, Staresinic M, Seiwerth S, Sikiric P. Gastric pentadecapeptide BPC 157 effective against serotonin syndrome in rats. European Journal of Pharmacology. 2005;512(2-3):173–179. DOI: 10.1016/j.ejphar.2005.02.038  ·  PubMed
  23. Madzarac G, Becejac T, Penovic T, et al. Tracheocutaneous Fistula Resolved by Pentadecapeptide BPC 157 Therapy Through the NO-System — Triple NO-Agent Approach in Rats. Pharmaceuticals (Basel). 2026;19(1):145. DOI: 10.3390/ph19010145  ·  PMC
  24. Sikiric P, Seiwerth S, Brcic L, Sever M, Klicek R, Radic B, Drmic D, Kolenc D, Vuksic T, Anic T. Focus on Ulcerative Colitis: Stable Gastric Pentadecapeptide BPC 157. Current Medicinal Chemistry. 2012;19(1):126–132. DOI: 10.2174/092986712803414015  ·  IngentaConnect